Serene Shereef, MD, FACS

SERENE SHEREEF, M.D, FACS.

CONTACT INFO: sshereef@gmail.com, (765) 490-7764

WORK EXPERIENCE:

Locums Surgical Coverage
General & Trauma Surgeon, Winchester, VA 07/2021-ongoing
General & Trauma Surgeon, Terre Haute, IN 02/2021-ongoing
General Surgeon, Madison, IN 9/2018-10/2019
07/2020-01/2021
General & Trauma Surgeon, Beavercreek, OH 11/2019-03/2020
General Surgeon, Enid, OK 07/2020
General Surgeon, LaPorte, IN 5/2019
Clinical Assistant Professor for the Indiana School West Lafayette, IN
of Medicine-WL at Purdue University 8/2018-12/2020
Clinical Instructor for Mind Body Wellness
– Clinical Coordinator & Instructor for Point of Care Ultrasound for Medical Students
– Clinical Instructor for Fundamentals of Clinical Practice for First & Second Year Medical
Students
– Clinical Instructor & Course Creation for Medical Student Wellness Curriculum
– Clinical Instructor for IUSM Transition to clinical medicine facilitator- Suture Lab
– Clinical Facilitator for Problem-based learning
– Clinical Coordinator & Facilitator for Intersessions
Indiana University Health Arnett Lafayette, IN
General, Breast, Trauma & Laparoscopic/DaVinci Surgeon 4/2015-4/2018
Private Practice Surgery Houston, TX
General, Breast & Laparoscopic Surgeon 9/2012-3/2015
Holy Spirit Hospital Camp Hill, PA
General Surgery Call Coverage 7/2007 – 6/2009
EDUCATION
Purdue Global University
Bachelors in Science-Health & Wellness 2019
Penn State College of Medicine Hershey, PA
Doctor of Medicine 2001-2005
University of Florida Gainesville, FL
Bachelor of Arts, Interdisciplinary Sciences 1999-2001
Minor, Modern Dance
Santa Fe Community College Gainesville, FL
Associate of Arts, General Sciences 1998-1999

INTERNSHIP AND RESIDENCY
Penn State Milton S. Hershey Medical Center Hershey, PA
General Surgery Intern 2005-2006
Penn State Milton S. Hershey Medical Center Hershey, PA
General Surgery Resident 2006 – 2012
Board Certified General Surgeon by American Board of Surgery Jan 2013 – 2023
Qualifying Examination 97th percentile national score
Fellow of American College of Surgeons October 2014
American Board of Surgery Maintenance of Certification Up To Date
HONORS AND AWARDS – PENN STATE COLLEGE OF MEDICINE
Doctors Kienle Center for Humanistic Medicine Resident Humanitarian Award 2010
Gold Humanism Honors Society 2004 – 2005
Department of Surgery Award For Excellence in Surgery 2005
Doctors Kienle Center for Humanistic Medicine Med Student Humanitarian Award 2004
Pathology Honors Society 2005
Danner Clouser Award for Medical Humanities Research 2002 – 2003
Ballantine Award for Healing Arts Project, Medical Humanities Project 2002 – 2003
MEMBERSHIP IN PROFESSIONAL SOCIETIES
American College of Surgeons – Fellow Member 2014-present
Lafayette Medical Education Foundation – Member 2017-2018
Indiana State Medical Association – Member 2016-2020
Tippecanoe County Medical Society – Member 2015-2021
TCMS Board Member – Secretary 2015-2021
The American Society of Breast Surgeons – Active Member 2013-2020
Society of American Gastrointestinal and Endoscopic Surgeons – Active Member 2013-2016
American College of Surgeons – Associate Member 2012 – 2014
Harris County Medical Society – Member 2012-2015
Young Physicians Ambassador HCMS SW Branch 2013-2015
HCMS Community Health Improvement & Communications Committee 2014-2015
HCMS Membership Committee 2014-2015
HCMS Strategic Planning Retreat Sept. 28 2013
Texas Medical Association – Member 2012-2015
Association of Surgical Education – Resident Member 2009 – 2010
American Association for Cancer Research, Associate Member 2008 – 2009
Pennsylvania State Women Surgeons Association – Vice President 2008 – 2010
Pennsylvania State Women Surgeons Association – Member 2006 – 2010
American Hepato-Pancreato-Biliary Association – Candidate Member 2007 – 2010
Association of Academic Surgeons – Candidate Member 2007 – 2010
American College of Surgeons – Resident Member 2005 – 2012

SERVICE ACTIVITIES
IUHA Physician Group Council Member – Elected position 2017-2018
Breast Program Leadership Committee Member 2016-2018
Breast Cancer Conference-Quality Review, IU Hospital Arnett 2015-2017
ACS CoC Cancer Liaison Physician (CLP) at Indiana University Health Arnett 2016-2017
Cancer Registry Quality Coordinator, IU Hospital Arnett 2015
Vice Chair, Department of Surgery, West Houston Medical Center 2014– 2015
Continuing Medical Education Committee member 2013 – 2015
Pharmacy and Therapeutics Committee member 2014 – 2015
Infectious Disease Committee member 2014 – 2015
MedSend Student Coordinator and Co-Founder 2003 – 2005
Organizing surgical/medical supplies to be sent to underprivileged populations
Institutional Review Board Member 2002 – 2003
Institutional Review Board Alternate 2003 – 2004
Wild Onions 4th Year Student Editor/Coordinator 2004 – 2005
Wild Onions Student Editor 2001 – 2004
Project coordinator for “Reach Out and Show you Care” -community
outreach by the Gold Humanism Honors Society at Pennsylvania State
University College of Medicine/Hershey Medical Center 2004-2005
EDUCATION / TEACHING EXPERIENCES
Graduate Medical Education
IUHA General Surgery Clerkship Director, Indiana University School of Medicine 2016-2018
– coordinating/facilitating all med student activities
Hospital Medical Education summer program/placement for Gen Surg 2016-2018
IU School of Medicine’s first Clerkship Leader Summit Participant May, 2017
IUPUI Site Clerkship Directors Meetings 2017-2018
Clinical Facilitator for Problem Based Learning, 2nd Year Medical Students IUSM at Purdue 2016-2017
– prep/presentation for 2nd yr med students – short bowel syndrome, lower abdominal pain, GI bleed
Clinical Mentor for 2nd year medical student (weekly shadowing, teaching in clinic/OR) 2016-2017
Lectures for 2nd year Med students, IUSM-Small bowel, large bowel 2016-2017
Robotic Surgery Certification 10/2014
Mini-Fellowship Course in Surgery (Complex Ventral Hernia Repair)
at University Hospitals Case Medical Center 12/2/2013
Minimally Invasive Colectomy Preceptorship & lab at Methodist Hosp 08/2013
Residents Teaching Residents Instructor 2010 – 2012
Penn State Graduate Medical Education Committee Member 2008 – 2012
Penn State College of Medicine Surgical Education Committee Member 2007 – 2011
Advanced Trauma Life Support (ATLS) Instructor 2008 – present
ATLS Instructor for Penn State Hershey Medical Center 2008-2012
ATLS Instructor for Memorial Hermann Hospital 2014-2015
ATLS Instructor for IU Methodist Trauma Program 2018-2021
General Surgery Curriculum, Intern Skills Sessions Facilitator 2007 – 2012
Residents as Teachers and Leaders, American College of Surgeons Course 2009

General Surgery Resident Education:
Erdahl L., Ratdka JF., Shereef S. “Intro of CBL and SCORE.” General Surgery Residency Core
Curriculum for Dept of Surgery, Hershey, PA, July 2, 2009.
Shereef S. “Residents Teaching Residents”. General Surgery Residency Core Curriculum for Dept
of Surgery, Hershey, PA, January 7, 2010.
Shereef S. “Senior Absite Review”. General Surgery Residency Core Curriculum for Dept of
Surgery, Hershey, PA, January 14, 2010.
Shereef S. “Residents Teaching Residents” General Surgery Residency Core Curriculum, Dept of
Surgery, July 22, 2010, Hershey, PA.
Shereef S. “R3, R4, R5: ABSITE Review” General Surgery Residency Core Curriculum, Dept of
Surgery, November 4, 2010, Hershey, PA.
Shereef S. “Residents Teaching Residents” General Surgery Residency Core Curriculum, Dept of
Surgery, March 31, 2011, Hershey, PA.
Shereef S. “Residents Teaching Residents” General Surgery Residency Core Curriculum, Dept of
Surgery, June 23, 2011, Hershey, PA.
Shereef S. “R1-R5: SESAP” General Surgery Residency Core Curriculum, Dept of Surgery, July 21,
2011, Hershey, PA.
Shereef S. “R1: Fundamentals of Surgery” General Surgery Residency Core Curriculum, Dept of
Surgery, July 28, 2011, Hershey, PA.
Shereef S. “R1-R5: SESAP” General Surgery Residency Core Curriculum, Dept of Surgery, August
18, 2011, Hershey, PA.
Shereef S. “ABSITE Overview” General Surgery Residency Core Curriculum, Dept of Surgery,
October 13, 2011, Hershey, PA.
Shereef S, Chestnut. “R1-R2: ABSITE Intro” General Surgery Residency Core Curriculum, Dept of
Surgery, November 10, 2011, Hershey, PA.
Shereef S. “Residents Teaching Residents” General Surgery Residency Core Curriculum, Dept of
Surgery, February 23, 2012, Hershey, PA.
Shereef S. “Vascular surgery case-based learning” General Surgery Residency Core Curriculum,
Dept of Surgery, March 15th, 2012, Hershey, PA.Undergraduate Medical Education
Pennsylvania State University, College of Medicine, Problem Based Learning Facilitator –
Endocrine, GI, Biologic Basis in Disease 2008-2009
Penn State College of Medicine, Clinical Skills Week Facilitator
NG tube placement, Central Line Placement, Suturing and Knot Tying 2008
Penn State College of Medicine, Surgery Clerkship Case Presentation 2008-2009
Penn State College of Medicine, Surgery Clerkship Skills Sessions Instructor 2007-2009
Anatomy Tutor for First Year Medical Students 2007, 2009

PUBLICATIONS
1. Avella DM. Li G. Schell TD. Liu D. Zhang SS. Lou X. Berg A. Kimchi ET. Tagaram HR. Yang Q.
Shereef S. Garcia LS. Kester M. Isom HC. Rountree CB. Staveley-O’Carroll KF. “Regression of
established hepatocellular carcinoma is induced by chemoimmunotherapy in an orthotopic
murine model.” Hepatology. 2012 Jan; 55(1):141-52.
2. Avella D, Garcia L, Gusani NJ, Nikfarjam M, Shereef S, Kimchi ET, Staveley-O’Carroll KF.
“Human acellular dermal matrix: an innovative tool for diaphragmatic reconstruction in patients
with large intra-abdominal tumors.” Am J Surg. 2010 Jan;199(1):e12-6.
3. Nikfarjam M, Kimchi ET, Gusani NJ, Shereef S, Avella DM, Staveley-O’Carroll KF. Reduction of
surgical site infections by use of pulsed irrigating device after prolonged intra-abdominal
operative procedures. J Surg Res. 2009;151(2): 291-292.
4. Nikfarjam M, Kimchi ET, Gusani NJ, Avella DM, Shereef S, Staveley-O’Carroll KF. Reduction of
surgical site infections by use of pulsatile lavage irrigation after prolonged intra-abdominal
surgical procedures. Am J Surg. 2009 Sep;198(3):381-6.
5. Nikfarjam M, Kimchi ET, Gusani NJ, Shah SM, Sehmbey M, Shereef S, Staveley-O’Carroll KF. A
reduction in delayed gastric emptying by classic pancreaticoduodenectomy with an antecolic
gastrojejunal anastomosis and a retrogastric omental patch. J Gastrointest Surg. 2009
Sep;13(9):1674-82.
6. Nikfarjam M, Shereef S, Kimchi E, Gusani N, Jiang Y, Liang J, Avella D, Mahraj R, Staveley-
O’Carroll K. Survival outcomes of patients with colorectal liver metastases following hepatic
resection or ablation in the era of effective chemotherapy. Ann Surg Oncol. 2009 Jul;16(7):1860-7.
7. Nikfarjam M, Sehmbey M, Kimchi ET, Gusani NJ, Shereef S, Avella DM, Staveley-O’Carroll KF.
Additional organ resection combined with pancreaticoduodenectomy does not increase post-
operative morbidity and mortality. Journal of Gastrointestinal Surgery 2009 May;13(5):915-21.
8. Avella D, Garcia L, Nikfarjam M, Shereef S, Gusani N, Kimchi E, Staveley-O’Carroll K. Alloderm
mesh an innovative tool for diaphragmatic reconstruction in patients with large retroperitoneal
sarcomas. J Surg Res. 2008;144(2):347.
9. Garcia L, Smith P, Avella D, Tagaram H, Jiang Y, Shereef S, Kimchi E, Staveley-O’Carroll K. MTD2
mice provide an excellent model for in vivo adoptive transfer studies to evaluate the tumor antigen
specific T cell response to hepatocellular cancer. J Surg Res. 2008;144(2):386.
10. Nikfarjam M, Kimchi E, Shereef S, Gusani N, Jiang Y, Liang J, Sehmbey M, Staveley-O’Carroll K.
Surgical outcomes of patient with gastrointestinal stromal tumors in the era of targeted drug
therapy. J Gastrointest Surg. 2008;12(11):2023-2031.
11. Shereef S. Lymphadenopathy. In: Kahan S, Smith E, Raves J, eds. In a page: signs & symptoms. San
Francisco, CA: John Wiley & Sons Inc. (formerly Blackwell Publishing);2004:103.
12. Cilley RE, Shereef S. Umbilical hernia repair. Operat Techn Gen Surg. 2004;6(4):244-252.

ABSTRACTS
1. Nikfarjam M., MD, PhD, Sehmbey M., B.Sc., Kimchi E., MD, Gusani N., MD, Shereef S., MD,
Staveley-o’carroll K., MD, PhD. Additional organ resection combined with pancreaticoduodenectomy does not
increase post-operative morbidity and mortality. Annual Congress of American Hepato PancreatoBiliarY
Association. March 12-15, 2009. Miami Beach, FL.
2. Avella D. MD, Garcia L. MD, Shereef S. MD, Tagaram H. PhD, Jiang Y. MD, PhD, Nikfarjam, M.
MD, Gusani N. MD, Kimchi E. MD, Staveley-O’Carroll K. MD, PhD. Immunologic Ignorance and
Tolerance Both Play a Role in Hepatic Tumorigenesis. The Society for Surgery of the Alimentary Tract. May
2008. Annual Meeting Abstracts. San Diego, CA.
3. Avella D. MD, Tagaram H. PhD, Sehmbey M, Garcia L. MD, Shereef S. MD, Kimchi E. MD, Zagon
I. PhD, McLaughlin P. SD, Staveley-O’Carroll K. MD, PhD. Opioid Growth Factor Mediated Inhibition of
Hepatic Carcinoma in vitro. Annual Congress of American Hepato Pancreato Biliary Association.
March 27-30, 2008. Fort Lauderdale. FL.
4. Shereef S. MD, Avella D. MD, Garcia L. MD, Tagaram H. PhD, Gusani N. MD, Nikfarjam M. MD,
Kimchi E. MD, Staveley-O’Carroll K. MD, PhD. Magnetic Resonance Imaging is a powerful tool for
characterizing the impact of Radiofrequency Ablation in a Murine model of Spontaneous Hepatocellular Cancer.
Annual Congress of American Hepato Pancreato BiliarY Association. March 27-30, 2008. Fort
Lauderdale. FL.
5. Garcia L. MD, Avella D. MD, Shereef S. MD, Tagaram H. PhD, Kimchi E. MD, Staveley-O’Carroll K.
MD, PhD. MTD2 Mice Provide an Excellent Model for in vivo Adoptive Transfer Studies to Evaluate the Tumor
Antigen Specific T cell Response to Hepatocellular Cancer. Association for Academic Surgery. 3rd Annual
Academic Surgical Congress. February 12-15, 2008. Huntington Beach. CA.
6. Avella D. MD, Garcia L. MD, Shereef S. MD, Tagaram H. PhD, Jiang Y. MD, PhD, Kimchi E. MD,
Staveley-O’Carroll K. MD, PhD. Tumor Growth in the liver depends on antigen load and immunologic ignorance.
Annual Congress of International Society of Gastrointestinal Oncology. September 27-29, 2007.
Philadelphia. PA
7. Garcia L. MD, Avella D. MD, Shereef S. MD, Tagaram H. PhD, Mosher T. MD, Kimchi E. MD,
Staveley-O’Carroll K. MD, PhD. Contrast Enhanced Magnetic Resonance Imaging: A Reliable Method to
Evaluate Tumor Progression/Regression in a Murine Model of Hepatocellular cancer. Annual congress of
International Society of Gastrointestinal Oncology. September 27-29, 2007. Philadelphia. PA

PRESENTATIONS
1. Nikfarjam M, M.D, PhD, Kimchi E, M.D, Gusani N, M.D, Shereef S, M.D, Avella D M.D, Sehmbey
M M.D, Staveley-O’Carroll K, M.D, PhD. Reduced delayed gastric emptying by classic
pancreaticoduodenectomy with an antecolic gastrojejunal anastomosis and a retrogastric omental
patch. Pancreas Club Meeting. Submitted.
2. Shereef S. MD, Nikfarjam M. MD, Avella D. MD, Gusani N. MD, Staveley-O’Carroll K. MD, PhD,
Conter R. MD, Kimchi E. MD. Castleman’s disease: A Diagnostic and Therapeutic Challenge. Association
for Academic Surgery. 4th Annual Academic Surgical Congress. February 3-6, 2009. Sanibel
Harbour, FL.
3. Shereef S. MD, Avella D. MD, Garcia L. MD, Tagaram H. PhD, Gusani N. MD, Nikfarjam M. MD,
Kimchi E. MD, Staveley-O’Carroll K. MD, PhD. Necrotic Cell Death by Radiofrequency Ablation releases
Heat Shock Protein. Association for Academic Surgery. 4th Annual Academic Surgical Congress.
February 3-6, 2009. Sanibel Harbour, FL.
4. Avella D. MD, Tagaram H. PhD, Shereef S. MD, Kimchi E. MD, Staveley-O’Carroll K. MD, PhD.
Tumor Neo-Angiogenesis is a Key Factor in the Induction of Tumor-Specific T-Cell Tolerance. Association for
Academic Surgery. 4th Annual Academic Surgical Congress. February 3-6, 2009. Sanibel Harbour,
FL.
5. Avella D. MD, Garcia L. MD, Tagaram H. PhD, Shereef S. MD, Jiang Y. MD, PhD, Nikfarjam, M.
MD, PhD, Gusani, N. MD, Kimchi E. MD, Staveley-O’Carroll K. MD, PhD. Immunologic ignorance and
tolerance both play a role in hepatic tumorigenesis. Society for Surgery of the Alimentary Tract (SSAT).
Digestive Diseases Week 2008. May 17-22, 2008. San Diego, CA.
6. Avella D. MD, Garcia L. MD, Shereef S. MD, Nikfarjam M. MD, PhD, Gusani N. MD Kimchi E.
MD, Staveley-O’Carroll K. MD, PhD. Alloderm Mesh: An Innovative Tool for Diaphragmatic Reconstruction
in Patients with large retroperitoneal Sarcomas. Association for Academic Surgery. 3rd Annual Academic
Surgical Congress. February 12-15, 2008. Huntington Beach. CA.
7. Avella D. MD, Garcia L. MD, Shereef S. MD, Tagaram H. PhD, Jiang Y. MD, PhD, Kimchi E. MD,
Staveley-O’Carroll K. MD, PhD. Tumor Growth in the liver depends on antigen load and immunologic
ignorance. Annual Congress of International Society of Gastrointestinal Oncology. September 28-
29,2007. Philadelphia. PA.
RESEARCH GRANTS
Completed Research Support
CTSA Grant Dr. Kevin Staveley-O’Carroll (PI) 01/01/2008 – 12/31/2008
Role: Research Assistant
Title: Dissecting the Interaction between Radiofrequency ablation and Tumor Antigen-Specific
Immune Response In Hepatocellular Cancer: A Murine Model And A Human Protocol.
Project Goal: This study will evaluate if RFA reverses antigen-specific CD8+ T-cell tolerance in
a murine model of HCC and demonstrate the possible changes in the function and phenotype of
the infiltrating T cells. This study will also evaluate the T cell responses specific for HCC-
associated antigens following RFA in HCC patients.